Quantitative and qualitative adenosine perfusion magnetic resonance imaging for the detection of coronary artery disease at 3 Tesla

Methods Eighty-six patients with intermediate risk, angina pectoris, and suspected coronary artery disease were enrolled into the study. All patients were examined in a 3 T CMR system including functional imaging of the left ventricle, adenosine and rest perfusion imaging using a bolus of 0.075 mmol/kg gadolinium based contrast agent (Dotarem, Guerbet, France), respectively. CMR studies were performed within 1 week prior to invasive coronary angiography which included QCA and FFR. Myocardial perfusion reserve (MPR) was calculated and correlated to FFR. Visual analysis of the perfusion sequences were compared to QCA. All measurements were performed by two blinded and experienced observers in consensus.